WHO THIS MATERIAL IS FOR: Health professionals in functional and integrative medicine: mechanisms, indications, contraindications, doses described in the literature, monitoring and critical reading of the evidence.
Patients and the general public: the green FOR THE PATIENT boxes and Module 7 bring the same information in plain language, so that readers know what to ask and what to expect from treatment.
ATTENTION: Chelators are drugs with real risks, including fatal ones when the chemical form, the dose or the infusion rate is wrong. Indication, prescription and monitoring are the responsibility of a licensed health professional, within the scope of their legal competencies, with individual assessment of the patient.
FOR THE PATIENT: Be wary of any promise of a cure. Even authors who favor chelation state that it does not cure degenerative diseases; the aim is to improve the conditions for tissues to recover.
CRITICAL ALERT: During an infusion, tell the team immediately if you feel tingling around the mouth or in the hands, cramps, spasms, palpitations, dizziness or shortness of breath. These may be signs of a drop in blood calcium or of an allergic reaction.
Sources and method
- The source content consists of chapters 4 (Chelation), 5 (Hair Mineral Analysis) and 6 (Toxic Metals) of the book Medicina Ortomolecular: Fundamentos e Prática [Orthomolecular Medicine: Fundamentals and Practice], by Miguel Curto (Atheneu, 2015), reorganized, summarized in the e-book's own words and updated with package inserts, regulatory agency documents (FDA, CDC, ATSDR) and clinical trials published up to 2025.
- Where current literature diverges from the source text, the divergence is explicitly flagged: in the update notes throughout the text and, all together, in Table 24 of Module 17.
- The homeopathic descriptions and the use of potentized metals from the source book were left out, as they lack support from clinical studies; the behavioral patterns of hair mineral analysis are not used as a diagnostic criterion, as they lack independent validation.
- Module 19 brings together 36 scientific references, grouped into 7 topics, most with a link.
- The key to the evidence labels is Table 2 of the e-book (pages 6 and 7):
- [BQ] Established biochemistry and pharmacology, verifiable in textbooks and reference reviews
- [ECR] Published randomized controlled trial
- [REG] Approved package insert or regulatory/health agency document (FDA, CDC, ATSDR)
- [EM] Mechanistic extrapolation or preclinical study (in vitro, animal), without a dedicated clinical trial
- [TC] Clinical tradition and experience reported in the orthomolecular literature (source book), without a dedicated randomized controlled trial
- [CI] Contraindicated by existing evidence